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231 reviews

5 Reasons Nattokinase Is Used to Support Heart Health

On a heart health journey? Here's why adding Toku Flow to your routine can make a real difference.

231 reviews

5 Reasons Nattokinase Is Used to Support Heart Health

On a heart health journey? Here's why adding Toku Flow to your routine can make a real difference.

231 reviews

5 Reasons Nattokinase Is Used to Support Heart Health

On a heart health journey? Here's why adding Toku Flow to your routine can make a real difference.

1. Hearth Health Backed By Clinical Research

Nattokinase has been examined in long-term clinical research focused on cardiovascular structure and blood flow related markers.

In a 12-month study involving over 1,000 participants, when taking at 10,800 FU daily, nattokinase supplementation was associated with a:

  • 39.1% improvement in coronary plaque health (measured by coronary plaque score)

  • 25% improvement in carotid artery flexibility (measured by CCA-IMT)

  • 17.6% reduction in total cholesterol

  • 16.5% reduction in triglycerides


Rather than targeting symptoms, this research explored how nattokinase supports foundational cardiovascular processes over time.

2. Nattokinase Goes Beyond Just Cholesterol

Cholesterol is only one part of the heart health picture.

A more complete cardiovascular assessment often includes markers related to:

  • ApoB, which reflects the number of circulating lipoprotein particles

  • Blood viscosity and flow characteristics

  • Vascular inflammation and endothelial function

  • Overall circulatory efficiency


Nattokinase has been studied for its role in supporting systems connected to these broader processes, which is why it’s often discussed as part of a more holistic heart health approach rather than a cholesterol-focused one.

A Clinically Relevant Dose of Nattokinase

Not all nattokinase is created equal. In fact, many brands on the market are underdosed and not third party tested. Explore a high-potency nattokinase at 10,800 FU that is third party tested, free of fillers, and soy free.

Explore More

3. A Natural, Food-Derived Approach to Heart Health

Nattokinase was originally discovered in natto, a fermented Japanese food that has been part of traditional diets for over a thousand years.

Populations with regular natto consumption have long been associated with strong cardiovascular health, which led researchers to identify nattokinase as one of its most compelling enzymes.

Toku Flow offers a modern, convenient way to incorporate this Japanese enzyme into a daily routine without needing to consume natto itself.

Why this matters:
Some of the most trusted heart-supporting ingredients come from traditional foods, not synthetic trends.

4. Supports the Systems That Influence Blood Pressure

Blood pressure is shaped by multiple factors, including circulation, vascular tone, and arterial flexibility.


Nattokinase has been explored in research examining how it supports the underlying circulatory systems that influence healthy blood pressure levels already within the normal range, rather than acting as a direct or immediate intervention.

5. Designed for Long-Term, Daily Heart Support

Heart health is not built in weeks. It’s shaped by daily habits over years.

Nattokinase is non-stimulatory and commonly used in long-term wellness routines focused on consistent cardiovascular support rather than noticeable short-term effects.

1. Hearth Health Backed By Clinical Research

Nattokinase has been examined in long-term clinical research focused on cardiovascular structure and blood flow related markers.

In a 12-month study involving over 1,000 participants, when taking at 10,800 FU daily, nattokinase supplementation was associated with a:

  • 39.1% improvement in coronary plaque health (measured by coronary plaque score)

  • 25% improvement in carotid artery flexibility (measured by CCA-IMT)

  • 17.6% reduction in total cholesterol

  • 16.5% reduction in triglycerides


Rather than targeting symptoms, this research explored how nattokinase supports foundational cardiovascular processes over time.

2. Nattokinase Goes Beyond Just Cholesterol

Cholesterol is only one part of the heart health picture.

A more complete cardiovascular assessment often includes markers related to:

  • ApoB, which reflects the number of circulating lipoprotein particles

  • Blood viscosity and flow characteristics

  • Vascular inflammation and endothelial function

  • Overall circulatory efficiency


Nattokinase has been studied for its role in supporting systems connected to these broader processes, which is why it’s often discussed as part of a more holistic heart health approach rather than a cholesterol-focused one.

A Clinically Relevant Dose of Nattokinase

Not all nattokinase is created equal. In fact, many brands on the market are underdosed and not third party tested. Explore a high-potency nattokinase at 10,800 FU that is third party tested, free of fillers, and soy free.

Explore More

3. A Natural, Food-Derived Approach to Heart Health

Nattokinase was originally discovered in natto, a fermented Japanese food that has been part of traditional diets for over a thousand years.

Populations with regular natto consumption have long been associated with strong cardiovascular health, which led researchers to identify nattokinase as one of its most compelling enzymes.

Toku Flow offers a modern, convenient way to incorporate this Japanese enzyme into a daily routine without needing to consume natto itself.

Why this matters:
Some of the most trusted heart-supporting ingredients come from traditional foods, not synthetic trends.

4. Supports the Systems That Influence Blood Pressure

Blood pressure is shaped by multiple factors, including circulation, vascular tone, and arterial flexibility.


Nattokinase has been explored in research examining how it supports the underlying circulatory systems that influence healthy blood pressure levels already within the normal range, rather than acting as a direct or immediate intervention.

5. Designed for Long-Term, Daily Heart Support

Heart health is not built in weeks. It’s shaped by daily habits over years.

Nattokinase is non-stimulatory and commonly used in long-term wellness routines focused on consistent cardiovascular support rather than noticeable short-term effects.

Toku Flow 10,800 FU Nattokinase Supplement | Soy Free Powder

Toku Flow 10,800 FU Nattokinase Supplement | Soy Free Powder

Toku Flow | Nattokinase Supplement (10,800 FU) - Toku - Chocolate
Toku Flow | Nattokinase Supplement (10,800 FU) - Toku - Chocolate
Clinically Relevant Dose of Nattokinase. Available in Chocolate and Unflavored.
Toku Flow Nattokinase Supplement Review. Available in Chocolate and Unflavored.
Toku Flow | Nattokinase Supplement (10,800 FU) - Toku - Chocolate
Toku Flow | Nattokinase Supplement (10,800 FU) - Toku - Chocolate and Unflavored
Toku Flow | Nattokinase Supplement (10,800 FU) - Toku - Chocolate and Unflavored
Chocolate Fact Panel

High-Potency Nattokinase Supplement for Cardiovascular Health & Circulation

Toku Flow delivers 10,800 FU of clinical-grade nattokinase per daily sachet, paired with Vitamin K2 (MK-7) and oat beta-glucan for comprehensive cardiovascular support. Sourced from chickpea fermentation (soy-free), third-party tested, no fillers.

Toku Flow 10,800 FU Nattokinase Supplement | Soy Free Powder

High-Potency Nattokinase Supplement for Cardiovascular Health & Circulation

Toku Flow delivers 10,800 FU of clinical-grade nattokinase per daily sachet, paired with Vitamin K2 (MK-7) and oat beta-glucan for comprehensive cardiovascular support. Sourced from chickpea fermentation (soy-free), third-party tested, no fillers.

Days of Supply:90 days
Pick Flavor:Chocolate
Chocolate
CHOCOLATE
Unflavored
UNFLAVORED
Purchase Options
30 Day Money Back Guarantee
Free shipping on orders over $75
INGREDIENTS

CHOCOLATE: Gluten Free Oat Bran with Beta Glucans, Nattokinase from Fermented Chickpeas, Vitamin K2 (MK-7), Cocoa Powder, Organic Stevia Extract, Sea Salt, and Monk Fruit Extract.

UNFLAVORED: Gluten Free Oat Bran with Beta Glucans, Nattokinase from Fermented Chickpeas, Vitamin K2 (MK-7).

HOW TO USE

Flow can be easily stirred into any beverage, cold or warm (avoid blending in beverages hotter than 120°F). Consume in the morning or at night with or without food.

THE NO LIST
  • No sugar
  • No GMOs
  • No gluten
  • No glyphosate
  • No hormones 
  • No antibiotics 
  • No soy
  • No fat
  • No artificial additives
  • No natural or artificial colors or flavors
  • No corn
  • No oils 
  • No binders or anti-caking agents
CERTIFICATIONS & TESTING

Glyphosate Free

Soy Free

Manufactured using 3rd Party certified current Good Manufacturing Practices (cGMPs) in an NSF certified facility

Thoroughly tested for heavy metal contaminants, enzymatic activity, phthalates, BPA/BPS levels and microbiological analysis by third party, FDA-registered, ISO 17025 accredited laboratories


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See What People
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  • Inflammation Support
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“My test results below are comparing blood work from March 2025 vs September 2025...1 packet of Toku Flow daily...and no significant change in physical activity:
- Cholesterol total 110 (4.35% decrease)
- LDL 54 (14.29% decrease)
- HDL 39 (11.43% increase)
- ApoB 58 (7.94% decrease)
- Triglycerides 83 (1.19% decrease)”

Tom

Verified
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“Since I started using this product, my blood pressure has consistently been 120 ish over 80 ish. It has well surpassed any expectations.”

Geoffrey

Verified
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“I've also noticed that the nerve pain I typically have from a lumbar disc herniation is much milder than normal and seemed to get worse when I forgot to take it with me on vacation for several days in a row. Game changer all around!”

James C.

Verified
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"After taking statins and having horrible muscle cramps, I was very optimistic about this product. I am happy to say that my muscle cramps are gone. My blood pressure is fantastic."

Richard

Verified
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“I started taking Toku Flow about 2.5 months ago. My cholesterol #'s were increasing and i was worried i would end up on a statin which i didn't want to do. I recently took my blood tests and showed incredible improvement in almost all heart biomarkers!!! Some of my markers improved by over 30% which is wild in such a short period of time.”

Jared Toren

Verified
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"I've been taking Flow by TOKU for about a week now and have noticed a better level of energy and less drag. Looking forward to other benefits in time!"

Jeff R.

Verified
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"We have been taking Toku Flow for 3 weeks and have noticed a significant decrease in our blood pressure. We are now in the norm range for our age. So far, we are very pleased with the product."

Stephanie

Verified
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"Been on this stuff for almost 4 months now to address my high LDL and its made a big impact. My most recent labs had an LDL drop of 22, which is pretty incredible."

Anonymous

Verified
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“I woke up one day with chronic leg, feet, and toe pain. After an injury to my legs years ago I have suspected poor circulation. I know I have arthritis in my hips. I saw the ad for Toku Flow and decided to give it a try. I am on my second month and I can say there is great improvement. Only thing different I did was take this product. I will continue to take Toku Flow.”

Marlaena

Verified
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“This has great taste, I feel almost invincible after, a few weeks of this!”

Ben Bla

Verified
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"Since taking this, i've set mile time PRs with my running while keeping my heart rate lower, my workout recovery has drastically improved, and my overall energy throughout the day is a lot better than normal."

Patrick S.

Verified
Customer Reviews
4.8 Based on 231 Reviews
5 ★
86% 
198
4 ★
9% 
20
3 ★
4% 
10
2 ★
1% 
2
1 ★
0% 
1
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