While nattokinase itself has amazing benefits, many nattokinase supplements are underdosed, requiring you to take up to five servings (or even more) to reach clinically relevant levels. With Toku Flow, you're getting a full clinically relevant dose in one convenient serving, making it far more cost-effective compared to leading brands.

Additionally, we've included Vitamin K2 in its most effective form of MK-7, which has proven clinical synergy with nattokinase for enhanced cardiovascular support - something most other brands remove, adding extra cost if you supplement it separately.

Our formula also contains oat bran rich in beta-glucan, known to improve enzyme absorption and help regulate blood glucose, a critical aspect of comprehensive heart health.

Our nattokinase is soy-free, eliminating a common allergen concern.

We also avoid undisclosed fillers—a widespread issue in the market—by using our proprietary freeze-drying process to isolate the enzyme cleanly and effectively. Plus, we transparently publish third-party testing results to confirm our product's potency and fibrinolytic activity, as well as a number of other important quality testing markers that many leading brands fall short on.

Lastly, each of our servings is individually wrapped to maintain the highest possible potency right until consumption, ensuring you're always getting optimal freshness and efficacy.  Instead of requiring you to take dozens of pills per day, Toku Flow is a delicious, easy-to-consume daily powdered drink mix.

Traditional nattokinase is indeed extracted from natto, which is fermented soybeans. However, the active enzyme itself (nattokinase) can also be produced through fermentation using other legumes. At Toku, we use a specialized fermentation process with chickpeas instead of soybeans, allowing us to deliver pure, soy-free nattokinase. This provides all the cardiovascular benefits without the potential allergenicity of soy.

Oat bran is the outer layer of whole oat grains, which is naturally rich in dietary fiber, particularly beta-glucan. Beta-glucan is a type of soluble fiber well-known for its heart health benefits. Clinical studies have shown that beta-glucan helps reduce cholesterol levels by binding to cholesterol in the digestive system, facilitating its elimination from the body. It also assists in stabilizing blood sugar levels by slowing glucose absorption, which supports metabolic health. In Toku Flow, we include oat bran because beta-glucan not only enhances the absorption of our nattokinase enzyme but also provides these significant cardiovascular and metabolic health benefits, offering comprehensive support for overall heart health.

Vitamin K2 MK-7 (menaquinone-7) is a highly bioavailable form of vitamin K2, naturally found in fermented foods like natto. It’s especially important for heart health because it plays a critical role in calcium metabolism, helping direct calcium to the bones and teeth rather than allowing it to build up in arteries and soft tissues. Clinical studies have shown that regular intake of Vitamin K2 MK-7 supports arterial flexibility, reduces arterial stiffness, and promotes overall cardiovascular health. By pairing Vitamin K2 MK-7 with nattokinase in Toku Flow, we enhance the cardiovascular benefits, providing synergistic support for a healthier heart.

Our nattokinase stands apart because we use a proprietary, soy-free fermentation process with chickpeas, eliminating common allergens and improving purity. Unlike many cheaper sources, we provide a fully transparent and clinically effective dosage—verified by third-party testing—which ensures you actually receive the potency stated on the label. Additionally, our freeze-drying process preserves enzyme activity without fillers or additives, delivering superior absorption and cardiovascular benefits. Each serving is individually wrapped to prevent exposure to air, maintaining maximum potency and freshness until consumption.

Importantly, when you calculate the actual cost per dose of nattokinase combined with Vitamin K2 and oat bran (beta-glucan), Toku Flow is significantly more cost-effective than purchasing these ingredients separately, offering both convenience and savings.

You absolutely can! We highly recommend eating a whole-food diet as your primary strategy in preventing heart disease. We created Toku Flow as a delicious, easy-to-use supplement to complement and enhance your health journey. The average serving of natto contains around 1,400–2,000 FU of nattokinase, while Toku Flow provides 10,800 FU per serving, ensuring you achieve a clinically relevant dose and experience even greater benefits alongside your dietary choices.

We chose a powder sachet format for Toku Flow because it allows us to deliver a clinically effective dose in a single, convenient serving. Most nattokinase supplements require multiple capsules to achieve similar potency, meaning you’d have to take numerous pills daily. Additionally, our individually dosed sachets protect the powder from exposure to air until the moment of consumption, ensuring maximum potency, freshness, and effectiveness. The powdered formulation also improves absorption and allows us to include beneficial ingredients like Vitamin K2 and oat bran—something that’s difficult to achieve effectively in pill form. Plus, it tastes delicious, making daily heart health support enjoyable and easy.

Toku Flow can be taken either with food or on an empty stomach—it's equally effective and gentle.

Toku Flow can be taken at any time of day, with or without food—whenever it’s most convenient for your routine. Many customers prefer taking it in the morning to support cardiovascular health throughout the day, while others find that taking it at night helps improve circulation and supports overnight recovery. The key is consistency—taking it daily ensures optimal benefits.

Yes, you can mix Toku Flow with coffee.

The one thing to watch is temperature:

- Very hot liquids (above ~120°F / 49°C) can gradually degrade nattokinase.

- For best potency, let your coffee cool to a warm, comfortable drinking temperature first, then stir in Toku Flow.

Many people enjoy it this way daily (some mix it with coffee, tea, or even hot chocolate).

Generally, yes, but always consult with your healthcare provider, especially if you're on blood thinning medications or have existing health concerns.

Yes, nattokinase is safe for daily use. Side effects are rare and have not been reported, though people on blood-thinners or with bleeding disorders should consult a doctor first prior to taking Toku.

Certain people may experience mild GI discomfort in the first few days, especially if their body isn’t used to the amount or type of fiber (oat beta glucan) in the formula. This is usually a sign that your gut microbiome is adjusting, and it often resolves within a week or two as your system acclimates. In the meantime, we recommend:

• Staying well hydrated (fiber needs water to move smoothly through your system)
• Taking Toku with food, especially in the beginning
• Adjusting the dose — starting low (like ¼ tsp) and slowly building up can help your body ease into it.

Here are the reasons why Oat Beta Glucan may cause GI Distress:

1. Increased Fiber Load
2. Oat beta glucan is a soluble fiber. If someone’s diet is typically low in fiber, a sudden increase (Toku delivers 3g of oat bran, about 300mg of beta glucan) can temporarily disrupt digestion as the gut microbiota adjust.
3. Fermentation in the Colon
4. Beta glucans are fermented by gut bacteria, which produces short-chain fatty acids (a health benefit) but also gas and bloating in the early stages of introduction.
5. Individual Sensitivities
6. Some individuals may be more sensitive to soluble fibers due to conditions like IBS, SIBO, or a generally sluggish GI system.

Many people begin noticing benefits such as improved circulation, energy, and overall well-being within the first few weeks. However, for optimal cardiovascular benefits and to experience the full effects, consistent daily use for at least 3-6 months is recommended.